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Country: China (Mainland)
Business Type:Trading Company
Tel: +8619030197839
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Tel: +8619030197839
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URL: http://www.86-ss.com
Province/state: Hebei
City: Xingtai
Street: Hao Shun Hua Yue City
MaxCard:
CAS NO.77591-33-4
99%(1-100000000000)Gram
1.All inquiries will be replied within 12 hours.
2.Dedication to quality, supply& service.
3. Strictly on selecting raw materials.|
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6.Faster delivery:Sample order in stock and 3-7 days for bulk production.body p span span span span span
7.We have strong cooperation with DHL,TNT, UPS, FEDEX,EMS. Or you also can choose your own shipping forwarder.
8.After-Sale Service:
1) Interational Authorized Third-Party Test For The Products You DemandI
2) 30 Days Warranty of quality of goods.body p span span span span span
Overview
Thymosin β4 is a member of the thymosin β family. Thymosin β4 is composed of 43 amino acids and is hydrophilic.
Application prospects
The latest research shows that the expression level of acetic acid thymic β4 gene is positively correlated with cancer cell metastasis and is closely related to tumor apoptosis. This provides new ideas for finding new methods to treat cancer, and therefore has broad prospects for the development of new drugs.
Biological functions and mechanisms of action
Tβ4 is one of the main actin regulatory molecules in the human body. It has multiple biological functions and plays an extremely important role in physiological and pathological processes such as tissue regeneration, remodeling, wound healing, maintaining actin balance, tumor onset and metastasis, cell apoptosis, inflammation, angiogenesis, and hair follicle development. 1. Actin regulatory factor Actin accounts for about 10% of the total protein in non-muscle cells and is an important component required for cell structure, cell movement and wound healing. Tβ4 in cells is sufficient to block all actin and can participate in regulating the polymerization and depolymerization of actin. Tβ4 can bind to actin monomers at a ratio of 1:1 to prevent the formation of F-actin polymers. The binding of Tβ4 to actin is also accompanied by the dissociation of bound water. Its C-terminus binds to actin His-40, causing the conformation of actin monomers to change. The Tβ4 molecule contains an actin binding domain (LKKTET), which is the main electrostatic contact site. Its N-terminal pro-fragment can inhibit the polymerization of actin through steric hindrance. When acting alone, Tβ4 can inhibit the polymerization of actin and the exchange of nucleosides on actin. This is contrary to the effect of another actin binding protein Profiling, which can promote the exchange of ADP and ATP and accelerate the assembly of actin. Tβ4 and Profiling can synergistically regulate the assembly of actin. Tβ4 can regulate the conversion between G-actin and F-actin. It is reported that in highly mobile blood cells, the concentration of Tβ4 reaches 300pmol, while the concentration required for Tβ4 to bind to G-actin is less than 20pmol; when the concentration increases, Tβ4 reduces the ability of F-actin to depolymerize, which may be the reason why Tβ4 has the function of regulating the intracellular microfilament system.
Uses
Thymus β4 acetate has the following uses: 1. Thymus β4 and tumors Studies have shown that thymus β4 acetate is associated with a variety of tumors, including colon cancer, melanoma, fibrosarcoma, breast cancer, pancreatic cancer and lung cancer, and it can cooperate with multiple factors to promote tumor invasion and metastasis. 2. The role of thymus β4 in the repair of cardiac damage In the acute stage of myocardial infarction, a large number of myocardial cells are ischemic and necrotic, resulting in impaired cardiac function and eventually progressing to heart failure. Studies have confirmed that thymus β4 acetate has the effect of protecting myocardial cells.
Package
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materia
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
Our advantages:
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD. is located in xingtai City, Hebei Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.